Durable proteo-hybrid vesicles for the extended functional lifetime of membrane proteins in bionanotechnology† †Electronic supplementary information (ESI) available: Additional supporting data and experimental methods. See DOI: 10.1039/c6cc04207d Click here for additional data file.

نویسندگان

Sanobar Khan

Mengqiu Li

Stephen P. Muench

Lars J. C. Jeuken

Paul A. Beales

چکیده

The full capabilities of membrane proteins in bionanotechnology can only be realised through improvements in their reconstitution environments that combine biocompatibility to support function and durability for long term stability. We demonstrate that hybrid vesicles composed of natural phospholipids and synthetic diblock copolymers have the potential to achieve these criteria.

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منابع مشابه

Transformable H-bonds and conformation in compressed glucose† †Electronic supplementary information (ESI) available: Detailed experimental data; detailed structural data. CCDC 1033994–1034008. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4sc03588g Click here for additional data file. Click here for additional data file. Click here for additional data file. Click here for additional data file.

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Membrane flow patterns in multicomponent giant vesicles induced by alternating electric fields† †Electronic supplementary information (ESI) available: Vesicle preparation procedure, numerical calculations and confocal microscopy movies of domain motion. See DOI: 10.1039/b811876k Click here for additional data file. Click here for additional data file. Click here for additional data file. Click here for additional data file. Click here for additional data file.

Alternating electric (AC) fields induce circular patterns of lipid transport in membranes of giant vesicles. The flow is visualized by fluorescently labelled lipid domains.

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